Gemfibrozil, one of the fibrates, but not fenofibrate, interferes with statin glucuronidation, which may increase the risk of myopathydue to elevations in statin serum levels
Rosuvastatin Interactions
indicating that ABT-335 does not have a clinically significant pharmacokinetic interaction with rosuvastatin in humans
doi: 10
Objective To investigate whether fenofibrate as add-on to statin treatment reduce persistent cardiovascular risk in adults with metabolic syndrome in a real world setting
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2003
The study design was an open-label, randomized, multiple-dose, three-period, and six-sequence Rosuvastatin Prescription only Fenofibrate is effective at reducing triglyceride levels and increasing HDL cholesterol levels; however, it is less effective than statins at reducing LDL cholesterol levels
fenofibrate rosuvastatin
Drug interactions are reported among 364 people who take Rosuvastatin calcium and Fenofibrate
Rosuvastatin may interact with various dietary supplements Summary: Drug interactions are reported among 2,010 people who take Crestor and Fenofibrate
View Fenofibrate + Rosuvastatin's uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg
A total of 137 drugs are known to interact with fenofibrate: 21 major drug interactions (49 brand and generic names) 115 moderate drug interactions (752 brand and generic names) Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol in the blood
Azmacort
There is an increased risk of developing a severe muscle wasting side effect called rhabdomyolysis
Fenofibrate may further increase risk for rhabdomyolysis when added to optimal statin regimen to further decrease TG and increase HDLs
Reduce dose of concomitant coumarin oral anticoagulants
Drug-Interactions Studies Rosuvastatin clearance is not dependent on metabolism by cytochrome P450 3A4 to a clinically significant extent
In some cases, rhabdomyolysis can cause kidney damage and even death
In addition, patients with type 2 diabetes were reported to have increased intestinal cholesterol absorption mediated by the Niemann-Pick C1-like 1 (NPC1L1) protein 15 )
indigestion
Discuss with your healthcare professional the use of your medicine with food Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications
Pediatric patients with homozygous familial hypercholesterolemia: 20 mg/day for patients 7 to 17 years of age
Given the potency of rosuvastatin to lower LDL-C and fenofibrate's effectiveness in lowering TG, the use of this specific combination may be desirable in treating mixed dyslipidemia
In some cases, rhabdomyolysis can cause kidney Fenofibrate is used together with a proper diet to reduce and treat high cholesterol and triglyceride (fat-like substances) levels in the blood
Of the total drug interactions, 21 are major, 115 are moderate, and 1 is minor
Common side effects include liver problems, breathing problems, and stomach pain
Avoid or Use Alternate Drug
It is used to prevent cardiovascular disease and treat various types of hyperlipidemia
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Rosuvas F (20/160 mg) Tablet works by reducing the formation of cholesterol and fats in the body
Fenofibrate may further increase risk for rhabdomyolysis when added to optimal statin regimen to further decrease TG and increase HDLs
There are 105 drugs known to interact with gemfibrozil, along with 7 disease interactions, and 1 alcohol/food interaction
Drugs
use alternative or monitor CK, myopathy sx; max rosuvastatin dose 5 mg/day: combo may incr
Paxlovid (nirmaterlvir/ritonavir) is an antiviral medication authorized
2010 Jun;32(5):633-5
Fenofibrate, a peroxisome proliferator activated receptor-α agonist, has been suggested as an important treatment option in the management of dyslipidaemia owing to its effects on
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction
In conclusion, after 5 mg/day of rosuvastatin, the lipid profile in patients with diabetes or atherosclerotic vascular diseases with metabolic syndrome could be
Fenofibrate is used together with a proper diet to reduce and treat high cholesterol and triglyceride (fat-like substances) levels in the blood
However, the combined use of lipid-lowering drugs increases the incidence and severity of adverse events
Rosuvastatin is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol in the blood
DRUG INTERACTIONS: See also How to Use section
Azo Urinary Pain Relief
If you experience any muscle pain, tenderness or weakness, fever, and/or dark colored urine you should stop treatment and see you doctor at once
Rosuvastatin: After oral administration peak plasma levels occur 5 hours after dosing
Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein (P-gp) inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2
The risk
Rosuvastatin is used together with a proper diet to lower bad cholesterol (LDL) and triglycerides (fats) in the blood, and to increase your good cholesterol (HDL)
Additionally, clinical pharmacology, drug interactions and the effects of fenofibrate and simvastatin on metabolic variables and cardiovascular risk are briefly described
Rosuvastatin Simvastatin Using alcohol or tobacco with certain medicines may also cause interactions to occur
Pediatric patients with homozygous familial hypercholesterolemia: 20 mg/day for patients 7 to 17 years of age
The United Kingdom Prospective Diabetes Study showed that the level of low-density lipoprotein cholesterol (LDL-C) is the most important risk factor for cardiovascular events even in patients with type 2 diabetes 1)